Aditya Choudhary et al. Froin Syndrome. 1Aditya Choudhary, 2Manoj K Goyal, 3Manish Modi, 4Kanchan K Mukherjee, 5Chirag K Ahuja, 6Vivek Lal. Georges Froin (–), a French physician practising at the turn of the century, was the first to describe the xanthochromia and marked coagulation of. Froin Syndrome is characterized with xanthochromic CSF, high CSF protein content, complete blockage of CSF circulation. We reported our case of Froin.

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However, protein and glucose in the CSF are non-specific and not significant, and other parameters are investigated for the diagnosis and prognosis of neurologic disorders. This is an open-access article distributed vroin the terms of the Creative Commons Attribution Non-Commercial License http: Comparison and outcome analysis of patients with apical and non-apical takotsubo cardiomyopathy.

Indian J Med Sci. At the second spinal anesthesia for bladder-cancer follow-up surgery, lumbar spinal pressure was measured. This article is an orphanas no other articles link to it. We reported our case of Froin Syndrome, a quite rare entity, with zyndrome radiologic features and characteristics of CSF biochemistry in the light of literature. For example, protein concentration elevates 1 mg for per erythrocytes in subarachnoidal hemorrhage. Related articles in PubMed [Computer-aided diagnosis of Parkinson’s disease based on the stacked deep polynomial networks ensemble learning framework].


The patient underwent extensive diagnostic testing in search of a primary tumour outside the central nervous system. Close mobile search navigation Article navigation. This condition was considered to be investigated and anesthesia was abandoned.

In case of detecting abnormal CSF appearance in the course of lumbar punction done for spinal anesthesia, CSF samples should be sent to biochemistry and microbiology laboratories. Dry tap and spinal anesthesia. Sign In or Create an Account.

Froin’s syndrome

We postponed the operation and decided to take the patient to orthopedics ward in order to investigate. Pseudo-Froin’s syndrome on MRI”. Receive exclusive offers and updates from Oxford Academic.

Email alerts New issue alert. CSF material was obtained in a sterile way and samples were sent to biochemistry and microbiology laboratories for examination. Select your language of interest to view the total content in your interested language. Spectrophotometric analysis of xanthochromia is frin for distinction between a traumatic spinal tap and a true intracranial bleed in cases when a yellow color of the CSF is observed.

Yellow discoloration and coagulation of the CSF was first described in meningitis by Georges Froin in and in spinal tumours by Max Nonne, 3 hence the name Nonne-Froin sign. A lumbar computed tomography CT was non-contributory. View large Download slide. This page was last edited synddome 2 Augustat Adams RD, Victor M editors. Guidelines on routine cerebrospinal fluid analysis. Therefore, a tumor of the spine was a suspicious cause of the xanthochromia, and CSF evaluation was performed immediately after CSF collection.

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Introduction Georges Froin reported in that xanthochromic cerebrospinal fluid CSF and coagulation caused meningeal irritation. Cranial and spinal cervical, thoracal and lumbar MRI revealed an intramedullary mass lesion 63 x 13 mm in size at froi of T2-L1 spines T1 hypointense, T2 peripherally hyperintense.

This condition may also be seen in meningitidis and epidural abscesses. Retrieved from ” https: Picture is taken immediately after the CSF collection.

He had undergone operative correction to maintain the curvature of the spine. National Center for Biotechnology InformationU.

Froin’s syndrome – Wikipedia

Cerebrospinal fluid CSF was seen to be xanthochromic clear light yellow, citrine. These findings syndrkme radiologically consistent with extradural spinal mass. From Wikipedia, the free encyclopedia.

In the case discussed here, the patient had suffered from year paraplegia with newly-developed urinary bladder cancer and showed abnormal CSF characteristics at spinal anesthesia.

You can help Wikipedia by expanding it. This case was concluded syndro,e be Pseudo-Froin’s syndrome without abnormal neurological findings, simply caused by interruption of CSF flow due to thoracic spine destruction and dislocation.